S.M.A.R.T. TMS

A New Era of Targeted TMS

S.M.A.R.T. TMS represents the next evolution of transcranial magnetic stimulation — a data-driven, image-guided approach that goes beyond conventional “one-size-fits-all” protocols.

Developed by Bradley A. Jabour, M.D., this proprietary technique integrates advanced connectomic brain mapping with accelerated stimulation paradigms to identify and treat the precise networks involved in each patient’s symptoms.

It’s not just TMS — it’s Symptom-Mapped, Accelerated, and Precisely Targeted neuromodulation.

This enables us to deliver Symptom-Mapped, Accelerated, and Highly Precise stimulation protocols that adapt to your unique brain architecture.

How S.M.A.R.T. TMS Works

1. Whole-Brain Connectomic Mapping

Each patient begins with the SMART BRAIN SCAN, our advanced Whole Brain MRI that combines morphologic, angiographic, and functional imaging with connectomic analysis.

Using this data, we generate a personalized 3D brain connectivity model, showing how the patient’s cognitive, sensory, and emotional networks communicate. This map reveals not only structure but also how efficiently each network interacts — highlighting underactive or overactive regions associated with the person’s unique symptoms.

These detailed maps give clinicians a real-time visualization of the brain’s functional circuits, from the prefrontal executive regions to the auditory and limbic pathways.

2. Symptom Network Identification

Left: Connectome view of the "Anxiety" network. Right: Connectome view of "Inhibition/Suppression" network, often utilized in treating OCD. 

Next, our specialists analyze the individual’s connectivity data to identify the neural networks most relevant to their symptoms.

• For tinnitus, we often see overactive connections in the hearing and attention areas — the brain keeps “listening” even when there’s no sound.
• For migraines, we may find imbalances in the brain’s pain-control circuits that make it more sensitive to triggers.
• For executive or focus problems, we often see reduced communication between the thinking and control centers of the brain, affecting motivation, organization, and decision-making.

By identifying these specific network changes, S.M.A.R.T. TMS allows us to target the exact brain regions linked to your symptoms, rather than using a one-size-fits-all approach.

3. Precision Targeting and Accelerated Protocols

Once the target regions are identified, our clinical team designs a customized stimulation plan using an accelerated TMS protocol modeled after the SAINT framework.

• Stimulation is delivered to multiple personalized cortical sites rather than a single “standard” region.

• Sessions are condensed over days instead of weeks, allowing the brain’s networks to reorganize and synchronize more rapidly.

• Continuous monitoring of symptom and network response ensures the protocol is fine-tuned in real time.

This accelerated, precision-guided method often leads to faster onset of clinical improvement and a more robust, sustained response.

4. Tracking the Brain’s Response

Throughout treatment, we can quantify and visualize how the brain responds using follow-up imaging and cognitive metrics.
Changes in connectivity patterns and perfusion provide objective evidence of improvement — transforming TMS from a subjective therapy into a measurable, data-validated intervention.

Conditions Treated

S.M.A.R.T. TMS expands the therapeutic reach of TMS far beyond depression, with applications in:

• Anxiety & Depression – Re-balancing emotional control circuits and calming overactive limbic pathways for improved mood and resilience.
• Executive Dysfunction / ADHD Spectrum – Strengthening prefrontal and attention networks to boost focus, motivation, and cognitive control.
• Obsessive or Compulsive Thinking Patterns – Interrupting rigid connectivity loops to reduce intrusive thoughts and improve flexibility.
• Tinnitus – Calming hyperactive auditory and attention circuits that create persistent ringing or phantom sounds.
• Chronic Migraine – Rebalancing sensory and vascular control networks that contribute to pain sensitivity and migraine frequency.
• Post-Concussion Cognitive Fatigue – Restoring network efficiency to improve clarity, processing speed, and mental endurance.
• Alzheimer’s Disease / Mild Cognitive Impairment – Supporting memory and executive networks to enhance function and slow cognitive decline.

(Treatment candidacy is determined following brain mapping and clinical evaluation.)

Why Choose S.M.A.R.T. TMS